Is it normal to no longer know how to make friends?

I am a female and I have just recently graduated from highschool and made it to college. As a child and adolescent I was very friendly and sociable with everyone, and very popular. However as of highschool I was the girl who could get any guy, but couldn't seem to make one girl friend. Over a few years in school I've lost a lot of friends from mostly growing apart, or petty arguements, or some I just didn't want to associate with anymore because the obsessive drama that always seemed to occur around teenage girls. But apparently rumors started speading around about me and when all was said and done, I wasn't left with anyone. I currently have 3 male friends I can talk to on a regular basis and trust, but rarely see because of my boyfriend.I haven't been able to make a single girl friend despite my efforts since highschool. I dont know how to communicate, or go about the right conversations with girls I dont know yet, to become friendly with. I don't know how to approach most girls without feeling akward, or misplaced.I've tried many times to make efforts with old and new friends and attempts to make plans, but I always get blown off. Is this normal? I dont want to go through whats supposed to be my best years with no real friends by my side.