Is it normal for everybody to be ignorant?

Why do people treat me like shit and become distant or judge me if my personality reflects it? Whenever I make friends or even with family members, I'm considerate. They do it when its convenient, and not if it compromises who they are. As a kid it affected my self-esteem but I was too happy with my childhood to let it spoil my fun. Now that I'm older its harder to let people treat me a certain way because it affects my daily life. I'm nice and chill but I easily become defensive to protect myself from being hurt. I do let my guard down alot but people always become comfortable with being fucked up towards me. And its like they don't see anything wrong with it. Its draining. I had a family member come back into my life who I tried to be cool with but he talked shit me for reactions. Yet, I supported him when his mom passed. He called me fake because I became uninterested in him (didn't ignore or avoid him) but I placed my attention elsewhere. I'm scared I'll be alone if I cant take that from ppl.