Dental drug interactions

can anyone give me more information on the interaction I seem to get with trimipramine, atenolol and dental anesthetic...........I felt very peculiar and drunk.....a sensation of pending doom engulfed me and I started to panic.........the anesthetic did not numb the area............this experienced frightened me and I explained it to the dentist but he almost brushed it off saying I was anxious! I have spoken to him about it as I felt this was not the response I was expecting and I am not normally anxious at the dentist, although after that experience I am apprehensive that it might happen again and he will just think I am performing! if anyone has any ideas I would be very grateful to hear them, thanks.

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Comments ( 2 )
  • plainsight90

    What kind of procedure were you in for? SRP(deep cleaning), fillings, root canal, etc?

    Most local anesthetics used in dentistry have epinephrine. Epinephrine causes vasoconstriction in order to sustain the anesthetic in the area to be numb. Local anesthetics work better that way. However, since epi is pretty much adrenaline, it can get your blood pressure and pulse up too, which is normal. Lidocaine with epi is the typical anesthetic used, however others are available too (usually).

    Anyway, your dentist sounds like a douchebag if he simply ignored you. He should have figured out what the issue was, even if it was pure anxiety that caused your reaction.

    If it was a drug reaction to the epinephrine or the anesthetic itself, another anesthetic could have been used (prilocaine is available without epi for those who are intolerant and articaine is available for people who can't get numb with lidocaine).

    Or if it was simply anxiety and injectable anesthesia isn't doing it for you, he could have switched to nitrous oxide (gas).

    If you are switching to another dentist, I would get in touch with the old one and see what they used on you last time. Obviously, whatever they used isn't working, so it would be helpful to give your new dentist that info.

    Hope that kinda helps.

    Sources: I'm a dental hygienist who administers local anesthetic all the time.

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  • ReaperAJ

    tranquilisers and anaesthetics can have strange effects on people. Perhaps the combination of drugs created a panic attack. Any kind of drugs have a variety of side effects, so maybe you should google each one and try to google them as a combination and see what results you get. I would seriously recommend that you change your dentist though. Any doctor should listen to his patient and most particulary when it comes to signs of distress due to the intake of medications, the combination he used is probably not compatible with your system and using it again may just end up being fatal or having serious consequences. Please, change your dentist, this guy sounds like he's just in it for the money and doesn't actually have his patients best interests at heart.

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