I say loaded up when something is inside something else (like a car boot or cardboard box) because you're filling that thing and you fill something "up" but you never fill it down.
I say loaded down when something is on top of something else (usually something that can feel the sensation of weight, like a donkey or a person), in the same way I'd say weighed down, or tied down.
When we say up, we normally refer to how full something is. When we say down, we normally refer to the effect of weight or gravity (which acts in a downward direction).
Up or down?
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I say loaded up when something is inside something else (like a car boot or cardboard box) because you're filling that thing and you fill something "up" but you never fill it down.
I say loaded down when something is on top of something else (usually something that can feel the sensation of weight, like a donkey or a person), in the same way I'd say weighed down, or tied down.
When we say up, we normally refer to how full something is. When we say down, we normally refer to the effect of weight or gravity (which acts in a downward direction).