Should ephedrine be banned?

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  • Hate to do a coppy and past but:
    Adverse effects
    Adverse drug reactions (ADRs) are more common with systemic administration (e.g. injection or oral administration) compared to topical administration (e.g. nasal instillations). ADRs associated with ephedrine therapy include:[4]

    Cardiovascular: tachycardia, cardiac arrhythmias, Angina pectoris, vasoconstriction with hypertension
    Dermatological: flushing, sweating, acne vulgaris
    Gastrointestinal: nausea, appetite loss
    Genitourinary: increased urine output due to increased blood flow (difficulty urinating is not uncommon, as alpha-agonists such as ephedrine constrict the internal urethral sphincter, mimicking the effects of sympathetic nervous system stimulation)
    Nervous system:restlessness, confusion, insomnia, mild euphoria, mania/hallucinations (rare except in previously existing psychiatric conditions), delusions, formication (may be possible, but lacks documented evidence) paranoia, hostility, panic, agitation
    Respiratory: dyspnea, pulmonary edema
    Miscellaneous: dizziness, headache, tremor, hyperglycemic reactions
    The approved maximum daily dosage of ephedrine for use as a bronchodilator is 150mg, as specified on the packaging of the bronchodilator and expectorant combination, Bronkaid, made by Bayer pharmaceuticals.

    Overdose can lead to death, although the approved dose is not likely to cause severe reactions when used as directed.

    Ephedrine can also lead to damage of the brain receptors' over a period of high usage; this is because of its constant action on the neurochemicals. It also leads to high increase in blood pressure which over time can lead to damage in the blood vessels.

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    • Thanks for the info. I didn't know that it was still being used. This is good news.

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