Medicine Question: Drugs that can put you to sleep at night?

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  • Everyone is different, but here’s my take...

    OVER THE COUNTER
    - Diphenhydramine (Benadryl), worthless
    - Melatonin, worthless
    - Chamomile, worthless
    - CBD, somewhat effective at high doses
    - Valerian root, worthless
    - L-tryptophan, worthless

    PRESCRIPTION ONLY
    - Zolpidem (Ambien), the best as long as taken on an empty stomach and for no more than two consecutive nights, so good luck every 3rd night
    - Trazodone, worthless
    - Hydroxyzine, worthless
    - Seroquel, somewhat effective at high doses
    - Olanzapine, somewhat effective at high doses
    - Mirtazapine, very effective but has 24 hour half-life and will give a hangover sedative feeling
    - Doxepin, can be okay at no more than 6mg
    - Propranolol, worthless

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