Knowledge, universe

I'm very concerned with knowledge. I know I know little, but this is a worry for me.

It's not a matter of education, yet it's the fact that life nor science cannot answer everything.

I suppose this is (perhaps) somewhat religious in question, but that's not my intention.

I feel somewhat alone. We have the human race, and earthly animals (fact).

But is it normal to feel lonely in literally a universal sense?