Is it normal to be depressed even on meds?

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  • It's worth noting that it's not possible to form a tolerance to many medications. There are other reasons medication can stop working, however, and I don't know what specific medication the OP is on. So it could be tolerance, for all I know.

    Do they really recommend that you switch every few years? Every doctor I've had has refrained from changing my medication unless it's necessary. Switching medication can be an ordeal, and I don't see how avoiding the possibility of developing a tolerance would be worth it.

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    • Im currently on 4 meds and have had to change them every couple years. It probablly depends on the person but I seem to get immune to most of them after so long. Also some of them cause side effects after so long. An example is I was on abilify for a few years and was fine and then started having tardive dyskinesia symptoms and had to switch to something else (zyperixa and lithium). Ive also taken meds where I would keep getting immune and had to keep increasing the dose until the dose was no longer safe and switched meds.

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      • Ok, thanks for the info! I think it probably depends on the medication and the situation. I've been on two different SSRIs, and they never switch me unless there's a problem.

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