I must have grown intolerance much like any other medication taken for a long period. No, my situation has been fairly uneventful which is great but it just bothers me why I react differently. Thanks.
I already told bugsforbreakfast this, but I'll say it again: it is not possible to form a tolerance to all medication. It seems like a lot of people don't know that. For example, the effectiveness of acetaminophen (Tylenol) doesn't decrease with frequent use. I'm not sure about antidepressants. I know that there's a bit of evidence for tolerance in certain tricyclic antidepressants, but I'm not sure about SSRIs, which are more commonly used these days. I'll get back to you, if you like.
That said, brains are complicated, and it's possible for other factors to make it so that a medication is no longer effective for a patient, even when tolerance isn't possible. It's not always terribly predictable. Bodies change. Talk to your doctor about changing medication or increasing your dose. There's something to be said for both options.
That's correct but it is possible to be intolerant of anti-depressants. It's called Treatment Resistant Depression. I was just wondering why it was so sudden and whether anyone can relate to the situation. Hopefully, I would not have to increase my dosage as I was fine with my current one. Thanks for your reply.
Oh, I guess I wasn't very clear. I meant that for some medications, it's not possible to develop a tolerance *as a result of using them*. You could still become tolerant (or intolerant) as a result of other factors for such medications. It's just not quite the same as tolerance in habit forming drugs.
Is it normal to be depressed even on meds?
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I must have grown intolerance much like any other medication taken for a long period. No, my situation has been fairly uneventful which is great but it just bothers me why I react differently. Thanks.
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VioletTrees
10 years ago
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I already told bugsforbreakfast this, but I'll say it again: it is not possible to form a tolerance to all medication. It seems like a lot of people don't know that. For example, the effectiveness of acetaminophen (Tylenol) doesn't decrease with frequent use. I'm not sure about antidepressants. I know that there's a bit of evidence for tolerance in certain tricyclic antidepressants, but I'm not sure about SSRIs, which are more commonly used these days. I'll get back to you, if you like.
That said, brains are complicated, and it's possible for other factors to make it so that a medication is no longer effective for a patient, even when tolerance isn't possible. It's not always terribly predictable. Bodies change. Talk to your doctor about changing medication or increasing your dose. There's something to be said for both options.
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Anonymous Post Author
10 years ago
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That's correct but it is possible to be intolerant of anti-depressants. It's called Treatment Resistant Depression. I was just wondering why it was so sudden and whether anyone can relate to the situation. Hopefully, I would not have to increase my dosage as I was fine with my current one. Thanks for your reply.
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VioletTrees
10 years ago
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Oh, I guess I wasn't very clear. I meant that for some medications, it's not possible to develop a tolerance *as a result of using them*. You could still become tolerant (or intolerant) as a result of other factors for such medications. It's just not quite the same as tolerance in habit forming drugs.