Is it normal to be awkward and have almost no friends?

I consider myself as an awkward person because I sometimes talk too much to people who aren't interested in talking to me, have maybe two friends, feel anxiety everytime I walk in crowds of people or when I walk by myself somewhere in a shopping centre or at school. At school, most girls are very unfriendly and all they care about is make up, pretty clothes, being the sexiest and partying. I have tried being like that but it didn't work out for me. Again, I was too awkward. Most boys would never think of hitting on me. I can talk about sci-fi, philosophy and strange medicine subjects for hours and people don't seem to be interested.
Is anyone else feeling they're awkward? How can I stop being awkward?