Very, very hard to say. It could cause them to come up with great ideas or as you said, any of these drugs could easily cause your mind to go on a "tangent" where you forget all about the "task at hand". During these tangents, they would likely just get all introspective, start thinking about personal things, and just become annoyed by the person trying to keep them on task. However, they could potentially come up with something brilliant as well. However, I think the former is a more likely outcome
Could LSD taken by cancer researchers lead to breakthroughs?
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Very, very hard to say. It could cause them to come up with great ideas or as you said, any of these drugs could easily cause your mind to go on a "tangent" where you forget all about the "task at hand". During these tangents, they would likely just get all introspective, start thinking about personal things, and just become annoyed by the person trying to keep them on task. However, they could potentially come up with something brilliant as well. However, I think the former is a more likely outcome